Anne, duc de Joyeuse (born 1561, Joyeuse, France—died October 20, 1587, Coutras, France) was a French nobleman who became a leader of the Roman Catholic extremists opposing the Protestant Huguenots during the 16th-century Wars of Religion.

The eldest son of Guillaume, viscount de Joyeuse, Anne when very young was admitted to the royal court, where he carried the title of Marquis d’Arques (after one of his father’s lands). King Henry III, having just lost his former favourites, took a great liking to Anne and created him duc de Joyeuse (1581) with precedence over all other peers of the realm except for princes of the blood and certain sovereign families. Henry also made Anne admiral of France (1582) and governor of Normandy (1586) and married him to Marguerite de Lorraine-Vaudémont, the younger half sister of the queen consort. A champion of Roman Catholic reaction against Henri I de Montmorency’s tolerant policy toward the Huguenots in Languedoc, Anne led an army against the Huguenots in Guyenne and massacred some of them at Mont-Saint-Éloi. At this inopportune moment he was recalled to court because of the intrigues of jealous rivals, and, when he marched a second time against the Huguenot Henry of Navarre (the future Henry IV), he was captured and killed at Coutras.