Mamfe, town located in western Cameroon, at the head of navigation of the Cross River. Mamfe is situated about 31 miles (50 km) east of the Nigerian border and about 100 miles (160 km) north of the Gulf of Guinea. Palm oil and kernels, bananas, cocoa, coffee, quinine, hardwood, and rubber are marketed in the town, which is served by an airfield and a hospital. The tower of the Senior District Officer’s House, dating from the British colonial period (1911), has been preserved as a historical monument. Pop. (2015) 31,641.