Simón Pereyns (born c. 1535, Antwerp [now in Belgium]—died 1589, Puebla de los Angeles, Viceroyalty of New Spain [now Puebla, Mexico]) was a Flemish-born painter, one of the first European painters to produce significant work in New Spain (Mexico).
Simón Pereyns learned to paint in the Flemish Mannerist style in his native Antwerp. In 1558 he left Antwerp for Portugal and spent nine months in Lisbon working in the studio of a Portuguese painter. He next traveled to Spain, where he worked in both Toledo and Madrid, apparently employed by the court of Philip II. While in Spain he met Gastón de Peralta, the future viceroy of New Spain, who took Pereyns with him in 1566 to what is now Mexico.
On his arrival there Pereyns began to work in the Palace of the Viceroys, but Peralta was soon forced to return to Spain. Pereyns remained in New Spain and produced primarily religious works. He is perhaps best known for a painting of the Virgin of the Pardon, destroyed in a fire in Mexico City’s cathedral in 1967. The painting may be one he was forced to make after being denounced for heresy and tried by the Spanish Inquisition (see inquisition). Despite this experience and his subsequent difficulties with the Holy Office, Pereyns continued to fulfill religious commissions and made paintings for many churches throughout New Spain.
Pereyns often worked in collaboration with other artists, particularly the painter Andrés de la Concha. About 1586 Pereyns made the retable of Huejotzingo—the only retable he worked on that remains intact—with Concha, sculptor Pedro de Requena, and goldsmith Marcos de San Pedro. It includes scenes such as the Adoration of the Kings, the Adoration of the Shepherds, and the Resurrection. In these images, Pereyns reveals his Flemish training through his use of bluish tones and his Mannerism in the use of strong diagonal compositions and expressive gestures. Among his last works is the Saint Christopher, painted for the cathedral in Mexico City in 1588. It depicts St. Christopher carrying a tiny Christ Child across a rushing river.