Tepatitlán, city, northeastern Jalisco estado (state), west-central Mexico. On the central plateau and on the Acatic River, at 6,100 feet (1,860 metres) above sea level, Tepatitlán is an important agricultural, livestock-raising, commercial, and industrial centre. Corn (maize) and beans thrive in the temperate climate, as do cattle, pigs, and horses. Aviculture and apiculture are also practiced. The city originated as a 16th-century Spanish settlement and retains much of its colonial character. Tepatitlán is accessible by highway from Guadalajara, the state capital, to the west-southwest, and from Aguascalientes, the capital of Aguascalientes state, to the north-northeast. Pop. (2005) 82,975; (2010) 91,959.