Basilica of Guadalupe, Roman Catholic church that is the chief religious center of Mexico, located in Villa de Guadalupe Hidalgo, a northern neighborhood of Mexico City. The church was erected near the spot where four apparitions of the Virgin Mary are said to have been received by an Indigenous convert named Juan Diego in December 1531, with the command that a church be built in Mary’s honor. The last apparition resulted in a painted image on the inside of Juan Diego’s cloak that became known as Our Lady of Guadalupe. The entire incident did much to hasten the conversion of the Indigenous people of Mexico to Christianity. In 1754 a papal bull made the Virgin of Guadalupe the patroness and protector of New Spain, and in 1810 she became the symbol of the Mexican independence movement when the patriot-priest Miguel Hidalgo y Costilla raised her picture to his banner.
Each year, hundreds of thousands of pilgrims from all over the world come to the church, the holiest in Mexico, which was given the status of a basilica by Pope Pius X in 1904. The present church, or Old Basilica, was constructed on the site of an earlier 16th-century church and was finished in 1709. When this basilica became dangerous because of the sinking of its foundations, a modern structure called the New Basilica was built nearby; the original image of the Virgin of Guadalupe is now housed in the New Basilica.
Villa de Guadalupe Hidalgo itself was the site, on February 2, 1848, of the signing of the treaty between the United States and Mexico that ended the Mexican-American War.