Hyannis, unincorporated village in Barnstable city, southeastern Massachusetts, U.S., on the southern coast of Cape Cod. Its name is that of a local 17th-century Algonquian Indian chief. A popular summer beach and yachting resort with ferryboat services to Nantucket Island and Martha’s Vineyard, it is one of the cape’s main business centres and a shipping point for fish and cranberries. The village is the site of the John F. Kennedy Hyannis Museum. The family home of the president is in nearby Hyannis Port (Hyannisport).