penstemon, (genus Penstemon), genus herbaceous plants of the family Plantaginaceae (order Lamiales), containing about 270 species native to North America, particularly the western United States. The flowers are usually large and showy, tubular, and bilaterally symmetrical and have four fertile stamens and one sterile stamen (staminode). Many species and varieties are popular in home gardens. The colourful flowers are white, yellow, blue, purple, or scarlet.