Réthymno, town, dímos (municipality), and capital of the pereferiakí enótita (regional unit) of Réthymno, on the north coast of Crete, Greece. A town and port on Almyroú (Almiroú) Bay, it lies north of the ancient Mycenaean town of Rhithymna.
Réthymno was a stronghold during the Venetian period in the late Middle Ages, when it was called Retimo; its port shipped malmsey (malvasia) wine. The city was captured in 1645 by the Turks. In May 1941 German paratroops landed in and secured Réthymno during the battle with Commonwealth forces for control of Crete.
Réthymno trades in wheat, almonds, olive oil, and wine. West of the town is the small port of Georgioúpoli (Yeoryioúpolis), which has sandy beaches on the east. Pop. (2001) city, 28,959; mun., 47,272; (2011) city, 32,468; mun., 55,525.