Santa Rosa de Copán, city, northwestern Honduras. It is located in the highlands at 3,806 feet (1,160 metres) above sea level, near the Alash Higuito River, a tributary of the Mejocote.
Founded in the 18th century, it was called Los Llanos until 1812 and Los Llanos de Santa Rosa thereafter. In 1843 it received city status, and it took its present name in 1869. Santa Rosa is now the chief commercial centre of western Honduras. Major industries include tobacco blending and cigar making, sugar refining, and mat weaving; lumber, furniture, leather products, clothing, and beverages are also produced; antimony is mined in the vicinity. Santa Rosa is also a transportation centre, and highways lead in several directions toward centres in Honduras and El Salvador; it also has an airfield. Pop. (2001) 26,031; (2013) 48,485.