screwworm, Any of several North and South American blowfly species named for the screwlike appearance of the larva’s body, which is ringed with small spines. Screwworms attack livestock and other animals, including humans. The true screwworm (Cochliomyia hominivorax) and the secondary screwworm (Callitroga macellaria) develop in decaying flesh; they may also attack healthy tissue. Each female deposits 200–400 eggs near an open wound. The larvae burrow into the tissue and, when mature, drop to the ground to pupate. Severe infestations (myiasis) may kill the affected animal.