Sir James Sempill (born 1566—died February 1626, Paisley, Renfrewshire, Scot.) was a Scottish poet remembered for his satirical poem A picktooth for the Pope, or the packman’s paternoster (1630?), an antipapal dialogue between a peddler and a priest written in rhyming couplets. Born into a family of Scottish poets, he was reared with the young King James VI. He attended the University of St. Andrews and became Scottish ambassador to England (1599) and to France (1601). He was knighted in 1600.