Takatsuki, city, Ōsaka fu (urban prefecture), Honshu, Japan. It lies along the Yodo River, midway between Ōsaka and Kyōto. During the late Muromachi period (1338–1573), Takatsuki became a castle town, and an army engineers’ camp was established there in the late 19th century. The city’s industrialization was rapid after World War II; products include electrical appliances and pharmaceuticals. Pop. (2005) 351,826; (2010) 357,359.