Uintatherium, extinct genus of large, hoofed mammals found as fossils in North America and Asia in terrestrial deposits that date from the middle of the Eocene Epoch (55.8–33.9 million years ago). The size of a modern rhinoceros, Uintatherium was among the largest animals of its time. The limbs were strongly constructed to support the massive body. Three pairs of bony growths, or protuberances, were present on the skull, and the anterior pair may have supported prominent horns. The teeth were also distinctive: males of the genus possessed large, powerful canines; incisors were absent in the upper jaw but present in a reduced state in the lower; and the upper molars were characterized by V-shaped crests.