Berenice I (flourished c. 317–c. 275 bce) was the queen of ancient Egypt, wife of Ptolemy I Soter, and mother of Arsinoe II and Ptolemy II Philadelphus.
Berenice arrived in Egypt in the retinue of Eurydice, Ptolemy’s second queen, whom he married as part of a political agreement with her father, Antipater of Macedonia. About 317 Ptolemy married Berenice. Probably because she was not of royal blood, a genealogy was fabricated to make her a half sister of the king. In 308 Berenice gave birth to Ptolemy II Philadelphus, and in 290 Ptolemy made her queen of Egypt. In 285 Ptolemy II was made coregent and successor to his father, bypassing Eurydice’s children. Ptolemy II’s second wife was his sister, Arsinoe II, also the child of Berenice.