Bocas del Toro, town, northwestern Panama, at the southern tip of Colón Island in Almirante Bay of the Caribbean Sea. It was founded by African immigrants in the early 19th century and was destroyed by fire twice in the early 1900s. It was once a thriving banana port but now exports primarily cacao, coconuts, and plantains. It is an important regional commercial centre and is served by domestic airlines. Pop. (2000) 4,020; (2010) 7,366.