Diogo Cão (flourished 1480–86) was a Portuguese navigator and explorer.
Cão was the first European to discover the mouth of the Congo River (August 1482). There he set up a stone pillar to mark Portuguese overlordship of the area. Sailing a short way upstream, he found that the inhabitants along the banks appeared willing to trade. He then traveled southward along the present Angola coast and erected a second pillar at Cape Santa Maria (Monte Negro, 13°26′ S). Upon his return to Lisbon in 1484 he was ennobled by King John II, granted an annuity, and authorized to add two pillars to his coat of arms in memory of those he had erected. On a second voyage (1485–86) he reached Cape Cross, 21°50′ S, now in Namibia.