Spironolactone is a diuretic drug that is used to treat conditions related to edema, hypertension, and hormonal imbalances. Examples include cirrhosis, congestive heart failure, nephrotic syndrome (a sign of kidney malfunction), and primary hyperaldosteronism (Conn syndrome). It also is used to treat certain forms of acne, as well as hirsutism, and is used in transgender women as part of gender-affirming hormone therapy.
