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5-phosphoribose 1-pyrophosphate
chemical compound
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metabolism
- In metabolism: Pyrimidine ribonucleotides
…phosphate moiety (reaction [73]) from 5-phosphoribose 1-pyrophosphate (PRPP); PRPP, which is formed from ribose 5-phosphate and ATP, also initiates the pathways for biosynthesis of purine nucleotides and of histidine. The product loses carbon dioxide to yield the parent pyrimidine nucleotide, uridylic acid (UMP; reaction [73]).
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