adalimumab
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- bacteriophages
- In bacteriophage: Role in laboratory research
Adalimumab (Humira), used for the treatment of rheumatoid arthritis, was the first fully human antibody made via phage display to be approved by the U.S. Food and Drug Administration (approved in 2002). For their discoveries relating to phage display, Smith and Winter were awarded a…
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- In bacteriophage: Role in laboratory research
- human monoclonal antibodies
- In monoclonal antibody: Human monoclonal antibodies
Adalimumab was the first fully human monoclonal antibody developed through phage display to be approved for clinical use in human patients; it was approved in 2002 as a therapy for rheumatoid arthritis. An injectable humanized monoclonal antibody is available for prevention of severe respiratory syncytial…
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- In monoclonal antibody: Human monoclonal antibodies
work of
- Smith
- In George P. Smith
Adalimumab, the first human antibody therapy produced using phage display, was approved by the U.S. Food and Drug Administration in 2002 for the treatment of rheumatoid arthritis.
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- In George P. Smith
- Winter
- In Gregory P. Winter
…for use in humans was adalimumab (Humira), which was approved by the U.S. Food and Drug Administration in 2002 for the treatment of rheumatoid arthritis. The drug was later approved for the treatment of inflammatory bowel disease, psoriasis, and certain other inflammatory conditions.
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- In Gregory P. Winter