digestion
digestion, sequence by which food is broken down and chemically converted so that it can be absorbed by the cells of an organism and used to maintain vital bodily functions. This article summarizes the chemical actions of the digestive process. For details on the anatomy and physiology for specific digestive systems, see digestive system, human, and digestive system, invertebrate.
In order to sustain themselves, all organisms must obtain nutrients from the environment. Some nutrients serve as raw materials for the synthesis of cellular material; others (e.g., many vitamins) act as regulators of chemical reactions; and still others, upon oxidation, yield energy. Not all nutrients, however, are in a form suitable for immediate use by an organism; some must undergo physical and chemical changes before they can serve as energy or cell substance.
Through the act of eating, or ingestion, nutrients are taken from the environment. Many nutrient molecules are so large and complex that they must be split into smaller molecules before they can be used by the organism. This process of breaking down food into molecular particles of usable size and content is called digestion. Unusable components are expelled from the organism by a process called egestion, or excretion. Some plants, many microorganisms, and all animals perform these three functions—ingestion, digestion, and egestion (often grouped under the term alimentation)—but, as expected, the details differ considerably from group to group.
The problems associated with nutrient intake and processing differ greatly depending on whether the organism is autotrophic or heterotrophic. Autotrophic organisms can manufacture the large energy-rich organic compounds necessary for life from simple inorganic raw materials; consequently, they require only simple nutrients from the environment. By contrast, heterotrophic organisms cannot manufacture complex organic compounds from simple inorganic ones, and so they must obtain preformed organic molecules directly from the environment.
Green plants constitute by far the majority of the Earth’s autotrophic organisms. During the process of photosynthesis, plants use light energy to synthesize organic materials from carbon dioxide and water. Both compounds can be absorbed easily across the membranes of cells—in a typical land plant, carbon dioxide is absorbed from the air by leaf cells, and water is absorbed from the soil by root cells—and used directly in photosynthesis; i.e., neither of them requires digestion. The only other nutrients needed by most green plants are minerals such as nitrogen, phosphorus, and potassium, which also can be absorbed directly and require no digestion. There are, however, a few green plants (such as sundew, Venus’s-flytrap, and pitcher plant) that supplement their inorganic diet with organic compounds (particularly protein) obtained by trapping and digesting insects and other small animals.
Heterotrophy characterizes all animals, most microorganisms, and plants and plantlike organisms (e.g., fungi) that lack the pigment chlorophyll, which is necessary for photosynthesis. These organisms must ingest organic nutrients—carbohydrates, proteins, and fats—and, by digestion, rearrange them into a form suitable for their own particular needs.
Ingestion
As already explained, the nutrients obtained by most green plants are small inorganic molecules that can move with relative ease across cell membranes. Heterotrophic organisms such as bacteria and fungi, which require organic nutrients yet lack adaptations for ingesting bulk food, also rely on direct absorption of small nutrient molecules. Molecules of carbohydrates, proteins, or lipids, however, are too large and complex to move easily across cell membranes. Bacteria and fungi circumvent this by secreting digestive enzymes onto the food material; these enzymes catalyze the splitting of the large molecules into smaller units that are then absorbed into the cells. In other words, the bacteria and fungi perform extracellular digestion—digestion outside cells—before ingesting the food. This is often referred to as osmotrophic nutrition.
Like bacteria, protozoans are unicellular organisms, but their method of feeding is quite different. They ingest relatively large particles of food and carry out intracellular digestion (digestion inside cells) through a method of feeding called phagotrophic nutrition. Many protozoans also are osmotrophic to a lesser degree. Some organisms, such as amoebas, have pseudopodia (“false feet”) that flow around the food particle until it is completely enclosed in a membrane-bounded chamber called a food vacuole; this process is called phagocytosis. Other protozoans, such as paramecia, pinch off food vacuoles from the end of a prominent oral groove into which food particles are drawn by the beating of numerous small hairlike projections called cilia. In still other cases of phagotrophic nutrition, tiny particles of food adhere to the membranous surface of the cell, which then folds inward and is pinched off as a vacuole; this process is called pinocytosis. The food particles contained in vacuoles formed through phagocytosis or pinocytosis have not entered the cell in the fullest sense until they have been digested into molecules able to cross the membrane of the vacuole and become incorporated into the cellular substance. This is accomplished by enzyme-containing organelles called lysosomes, which fuse with the vacuoles and convert food into simpler compounds (see ).
Most multicellular animals possess some sort of digestive cavity—a chamber opening to the exterior via a mouth—in which digestion takes place. The higher animals, including the vertebrates, have more elaborate digestive tracts, or alimentary canals, through which food passes. In all of these systems large particles of food are broken down to units of more manageable size within the cavity before being taken into cells and reassembled (or assimilated) as cellular substance.