Ask the Chatbot Games & Quizzes ProCon History & Society Science & Tech Biographies Animals & Nature Geography & Travel Arts & Culture Money Videos
histone
Table of Contents
Introduction References & Edit History Related Topics
Images
centromere and chromatids in cell division DNA wraps around proteins called histones to form units known as nucleosomes. These units condense into a chromatin fibre, which condenses further to form a chromosome. Epigenetics studies have revealed that chemical modifications to histones can be inherited and define how the information in genes is expressed and used by cells. histone; nucleosome
Related Questions
Read Next
Molecular structure of a petide - sequence of amino acids
What Is the Difference Between a Peptide and a Protein?
Illustration of molecules. (molecular, chemistry, science)
Why Is a Group of Molecules Called a Mole?
molecule model, element
Molecular Machines: Making for the Future
Overhead view of high protein foods: chicken, meat, spinach, eggs, nuts, bean, cheese. (nutrition, health, food, diet)
Why Is Eating Protein Important?
Discover
Title: Senate Square, St. Petersburg, December 14, 1825: repression of the troop mutiny - watercolor by Carl Ivanovitch Kollman, 1825 depicts Decembrist uprising clashing with cavalry, with spectators watching. (new style December 26, 1825) Europe. Saint
8 of the Largest Empires in History
The Cheshire Cat is a fictional cat from Lewis Carroll's Alice's Adventures in Wonderland. (Alice in Wonderland)
11 Banned Books Through Time
An ancient egyptian hieroglyphic painted carving showing the falcon headed god Horus seated on a throne and holding a golden fly whisk. Before him are the Pharoah Seti and the goddess Isis. Interior wall of the temple to Osiris at Abydos, Egypt.
11 Egyptian Gods and Goddesses
Super Typhoon Noru over the western tropical Pacific Ocean as observed by the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA Aqua satellite July 31 2017
What Is the Difference Between a Typhoon and a Super Typhoon?
A human Inuit skull in a stone chambered cairn in Ilulissat in Greenland. These ancient graves are pre christian and are at least 2000
14 Tough Questions Answered
Santa Claus flying in his sleigh, christmas, reindeer
Was Santa Claus a Real Person?
A Factory Interior, watercolor, pen and gray ink, graphite, and white goache on wove paper by unknown artist, c. 1871-91; in the Yale Center for British Art. Industrial Revolution England
Inventors and Inventions of the Industrial Revolution

histone

biochemistry
verifiedCite
While every effort has been made to follow citation style rules, there may be some discrepancies. Please refer to the appropriate style manual or other sources if you have any questions.
Select Citation Style
Share
Share to social media
URL
https://www.britannica.com/science/histone
Feedback
Corrections? Updates? Omissions? Let us know if you have suggestions to improve this article (requires login).
Thank you for your feedback

Our editors will review what you’ve submitted and determine whether to revise the article.

External Websites
Written and fact-checked by
The Editors of Encyclopaedia Britannica
Encyclopaedia Britannica's editors oversee subject areas in which they have extensive knowledge, whether from years of experience gained by working on that content or via study for an advanced degree. They write new content and verify and edit content received from contributors.
The Editors of Encyclopaedia Britannica
Article History
Key People:
Venki Ramakrishnan
Related Topics:
protein
epigenomics
See all related content

histone, any of a group of simple alkaline proteins usually occurring in cell nuclei, combined ionically with DNA (deoxyribonucleic acid) to form nucleoproteins (q.v.). A unit in which a molecule of a histone is bound to a segment of the DNA chain of genetic material is termed a nucleosome. It has been suggested that changes in these units are associated with changes in the physical state and function of the chromatin during cell division and the transcription of the genetic message. Discovered in avian red blood cell nuclei by Albrecht Kossel about 1884, histones are water-soluble and contain large amounts of basic amino acids, particularly lysine and arginine. They are abundant in the thymus and pancreas.