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milieu intérieur

medicine

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Bernard’s concept of physiology

  • adenosine triphosphate; physiology
    In physiology: Historical background

    …as the internal environment (milieu intérieur) in which cells carry out their activities. This concept of physiological regulation of the internal environment occupies an important position in physiology and medicine; Bernard’s work had a profound influence on succeeding generations of physiologists in France, Russia, Italy, England, and the United…

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body heat, thermal energy that is a by-product of metabolism in higher animals, especially noticeable in birds and mammals, which exhibit a close control of their body temperature in the face of environmental fluctuation. Birds and mammals can conserve body heat by fluffing up feathers or erecting their hairs and by reducing blood flow to the exterior surface and extremities. They can increase body heat by shivering and exercise. Excessive body heat is dispelled chiefly by increasing blood flow to the surface and extremities, by sweating or panting, and by maximizing exposure of the body surface to the surroundings.

In humans, body heat is regulated to provide a normal temperature of 37° C (98.6° F). The brain stem, specifically the thermostatic region of the hypothalamus, is the centre of temperature regulation. When it becomes deranged, as during infections, heat is conserved unnecessarily and the temperature can exceed the normal range (see fever).