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sclerotome

anatomy

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skeleton

  • embryos of different animals
    In animal development: The body muscles and axial skeleton

    …of the somite, called the sclerotome, breaks up into mesenchyme, which contributes to the axial skeleton of the embryo—that is, the vertebral column, ribs, and much of the skull. The parietal layer of the somite, at a later stage, is converted into mesenchyme that, together with components of the neural…

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  • vertebrate: skeleton
    In skeleton: Embryology of vertebrate skeletons

    …a medial ventral mass, the sclerotome. The sclerotomic cells from each pair of somites migrate until they enclose the notochord, separating it from the neural tube dorsally and from the aorta (the principal blood vessel) ventrally. The sclerotomic tissue retains its original segmentation and condenses to form the forerunner, or…

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somite

  • In somite

    …of the somites arise the sclerotome, forerunner of the bodies and neural arches of the vertebrae; the dermatome, precursor of the connective tissue of the skin; and the myotome, or primitive muscle, from which the major muscles of vertebrates are derived. The term somite is also used more generally to…

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Related Topics:
somite

dermatome, the outer portion of an embryo from which the skin and subcutaneous tissues are developed and, postnatally, the areas of skin supplied by the branches of a single dorsal root ganglion (a dense group of nerve-cell bodies). In the developing embryo the dermatome arises from one of the three segments (somites) of the mesoderm, the middle layer of embryonic tissue.

Dermatomes are arranged with considerable regularity in the vertebrate trunk, although there is some overlap with similar areas above and below. Because each dermatomic area of skin is innervated by branches of nerves originating from a single dorsal root ganglion, the loss of sensation in an area of skin can be traced to a specific spinal nerve, facilitating the diagnosis of spinal cord injuries and certain neurological diseases.

This article was most recently revised and updated by Kara Rogers.