Related Topics:
nucleic acid
RNA
DNA

Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are complex molecular structures that control all hereditary characteristics of cells and thus of organisms. DNA is the master blueprint for life and constitutes the genetic material in all free-living organisms. RNA uses DNA to code for the structure of proteins synthesized in cells, and it is also the genetic material of certain viruses.

There are several chemical differences between the two structures. As the name deoxyribonucleic acid suggests, DNA has a sugar known as deoxyribose in the “backbone” of the molecule. Ribonucleic acid (RNA) has a slightly different sugar, known as ribose. Both are made of combinations of four nucleotides, which are special “building block” molecules with a nitrogen base. DNA is composed of long strands of the nucleotides adenine, guanine, cytosine, and thymine. In RNA, the thymine is replaced by uracil. The order and patterns of these nucleotides form the genetic code.

Physically, DNA is structured as a double helix, with two strands of DNA winding around each other, while RNA is structured as a single strand.

Melissa Petruzzello
Also called:
d-2-deoxyribose

deoxyribose, five-carbon sugar component of DNA (q.v.; deoxyribonucleic acid), where it alternates with phosphate groups to form the “backbone” of the DNA polymer and binds to nitrogenous bases. The presence of deoxyribose instead of ribose is one difference between DNA and RNA (ribonucleic acid). Deoxyribose was synthesized in 1935, but it was not isolated from DNA until 1954.