fertilization of human egg(1) The sperm release enzymes that help disperse the corona radiata and bind to the zona pellucida. (2) The outer sperm head layer is sloughed off, exposing enzymes that digest a path through the zona pellucida. (3) The sperm fuses with the egg cell membrane, causing the zona pellucida to become impenetrable to other sperm. (4) The tail separates from the sperm head, and the male pronucleus enlarges and travels to the female pronucleus in the center of the cell. Chromosomes merge to form a fertilized egg.
fertilization, Reproductive process in which a male sex cell (sperm) unites with a female sex cell (egg). During the process, the chromosomes of the egg and sperm will merge to form a zygote, which will divide to form an embryo. In humans, sperm travel from the vagina through the uterus to a fallopian tube, where they surround an egg released from an ovary usually two or three days earlier. Once one sperm has fused with the egg cell membrane, the outer layer becomes impenetrable to other sperm. See also cross-fertilization, self-fertilization.