Who is Sherlock Holmes’s nemesis?

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Sherlock Holmes’s greatest nemesis is Professor James Moriarty whom Holmes considers the “Napoleon of Crime.” The character of Professor Moriarty recurs in several detective stories and novels by Arthur Conan Doyle. Similar to Sherlock Holmes’s character having real-life inspiration, it is believed that Conan Doyle based Moriarty on Adam Worth, a real criminal who was active at the time.

Was Sherlock Holmes a real person?

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Sherlock Holmes is a fictional character created by the Scottish writer Arthur Conan Doyle. However, Conan Doyle did model Holmes’s methods and mannerisms on those of Dr. Joseph Bell, who had been his professor at the University of Edinburgh Medical School. Conan Doyle took inspiration from Bell’s method of diagnosing a patient’s disease.