Key People:
Henrietta Lacks
Related Topics:
tissue culture

HeLa cell, a cancerous cell belonging to a strain continuously cultured since its isolation in 1951 from a patient suffering from cervical carcinoma. The designation HeLa is derived from the name of the patient, Henrietta Lacks. HeLa cells were the first human cell line to be established and have been widely used in laboratory studies, especially in research on viruses, cancer, and human genetics.

HeLa cells are a common source of cross-contamination of other cell lines and a suspected cause of numerous instances of cell line misidentification. The HeLa cell genome has also been shown to be highly unstable, housing numerous genomic rearrangements (e.g., abnormal numbers of chromosomes) in a phenomenon known as chromothripsis.

This article was most recently revised and updated by Kara Rogers.
Related Topics:
tissue culture

cell culture, the maintenance and growth of the cells of multicellular organisms outside the body in specially designed containers and under precise conditions of temperature, humidity, nutrition, and freedom from contamination. In a broad sense, cells, tissues, and organs that are isolated and maintained in the laboratory are considered the objects of tissue culture. The techniques of cell culture have allowed scientists to use cultures of cells for experimental studies and for biological assays of many types. See tissue culture.

This article was most recently revised and updated by Amy Tikkanen.