RNA-induced silencing complex
biochemistry
Also known as: RISC
Learn about this topic in these articles:
role in RNA interference
- In RNA interference: RNAi in nature
…molecule then binds to an RNA-induced silencing complex (RISC), which contains multiple proteins, including a ribonuclease enzyme. The miRNA nucleotide sequence directs the protein complex to bind to a complementary sequence of mRNA. Once bound to the mRNA, the miRNA-RISC complex then enzymatically cleaves targeted sites on the mRNA molecule,…
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