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acute intermittent porphyria
pathology
Also known as: AIP, porphyria hepatica
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caused by metabolic disorder
- In metabolic disease: Porphyrias
One common form is acute intermittent porphyria, which is caused by a deficiency of the enzyme porphobilinogen deaminase. Symptoms usually arise during adolescence, and hormonal changes (e.g., menstruation), alcohol ingestion, certain foods, and some drugs may exacerbate the condition. Diagnosis is made by detecting porphyrins in the
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type of porphyria
- In porphyria
…of hepatic porphyria: (1) In acute intermittent porphyria, also called porphyria hepatica, affected persons have recurrent attacks of abdominal pain and vomiting, weakness or paralysis of the limbs, and psychic changes resembling hysteria. Attacks may be precipitated by a variety of drugs, including barbiturates and contraceptives and possibly alcohol. This…
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