alternative pathway

immunology

Also known as: properdin system

Learn about this topic in these articles:

In complement
…the lectin pathway, and the alternative pathway (or properdin system). A different type of signal activates each pathway. The classical pathway is triggered by groups of antibodies bound to the surfaces of a microorganism, while the lectin pathway is spurred into action by mannan-binding lectin, a constituent of serum that…
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In immune system: Activation of the complement system
…by antigen-antibody complexes; and the alternative pathway, which is triggered by other means, including invading pathogens or tumour cells. (The term alternative is something of a misnomer because this pathway almost certainly evolved before the classical pathway. The terminology reflects the order of discovery, not the evolutionary age of the…
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