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indirect-acting genotoxic carcinogen
biochemistry
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description and effects
- In poison: Carcinogenesis
Indirect-acting genotoxic carcinogens do not bind to DNA until they have been biotransformed in the body to reactive chemicals. Among the indirect-acting carcinogens, polycyclic aromatic hydrocarbons, nitrosamines, and nitrosonornicotine are found in cigarette smoke. Polycyclic aromatic hydrocarbons are also formed in charcoal-broiled meat. Nitrosamines can…
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