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monovalent oral poliovirus vaccine
medicine
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polio
- In polio: Treatment and vaccination
…of the three serotypes; and monovalent (mOPV), which contains one of the three serotypes. Thus, trivalent vaccine is effective against all three serotypes (PV1, PV2, and PV3), bivalent vaccine is effective against PV1 and PV3, and monovalent vaccines are effective against a single serotype. The specificity of mOPVs increases their…
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polio vaccine
- In polio vaccine
In contrast, monovalent OPV1 (mOPV1) contains live attenuated virus of only PV1 and thus is effective only against serotype 1. In general, for both IPV and OPV, three doses of vaccine are required, with a fourth (“booster”) given when a child reaches school age. Because PV2 dropped…
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