nucleoside reverse transcriptase inhibitor

drug

Also known as: NRTI

Learn about this topic in these articles:

In reverse transcriptase: Reverse transcriptase: discovery and impacts
Nucleoside reverse transcriptase inhibitors (NRTIs) such as AZT (zidovudine)—the first drug approved by the U.S. Food and Drug Administration to prolong the lives of AIDS patients—act by terminating the proviral DNA chain before the enzyme can finish transcription. NRTIs are often given in combination with…
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In AIDS: Antiretroviral medications
Nucleoside reverse transcriptase (RT) inhibitors (e.g., abacavir [ABC], zidovudine [AZT], zalcitabine [ddC], didanosine [ddI], stavudine [d4T], and lamivudine [3TC]) and non-nucleoside RT inhibitors (e.g., efavirenz, delavirdine, and nevirapine) both inhibit the action of reverse transcriptase. Each drug has unique side effects, and, in addition, treatment…
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