placental barrier
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drug action
- In drug: Reproductive system drugs
The so-called placental barrier and the blood-testis barrier impede certain chemicals, although both allow most fat-soluble chemicals to cross. Drugs that are more water-soluble and that possess higher molecular weights tend not to cross either the placental or the blood-testis barrier. In addition, if a drug binds…
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poisons and poisoning
- In poison: Role of distribution barriers
The placental barrier between mother and fetus is the “leakiest” barrier and is a very poor block to chemicals. The placenta is composed of several layers of cells acting as a barrier for the diffusion of substances between the maternal and fetal circulatory systems. Lipid-soluble molecules,…
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reagins
- In reagin
…heating, do not pass the placental barrier (i.e., an allergic mother cannot passively make her child allergic), and have a much longer life span than other types of antibodies. Reaginic antibodies can be transferred passively to a second person; thus, blood transfusions from allergic donors have occasionally produced temporary identical…
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