pyridostigmine

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pyridostigmine

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cholinergic drugs

In cholinergic drug
Neostigmine and pyridostigmine are drugs that can access the neuromuscular junction, but they cannot enter the ganglia of the autonomic nervous system and thus do not cross the blood-brain barrier. Therefore, these agents prolong the action of acetylcholine specifically at the neuromuscular junction.
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treatment of myasthenia gravis

In drug: Drugs that affect skeletal muscle
Neostigmine and pyridostigmine are the drugs most often used, because they appear to have a greater effect on neuromuscular transmission than on other cholinergic synapses, and this produces fewer unwanted side effects. The immune mechanism responsible for the inappropriate production of antibodies against the acetylcholine receptor is…
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