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transient receptor potential subfamily A
biochemistry
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role in thermoreception and response
- In thermoreception: Study of thermoreceptors
…channels known as TRPM (melastatin), TRPA (subfamily A), and TRPV (vanilloid) can respond to changes in temperature, with TRPM and TRPA known to respond to cold and TRPV known to respond to warmth, noxious heat, and protons. TRPV channels have been identified on sensory neurons and on epithelial cells, and…
Read More - In thermoreception: Properties of thermoreceptors
…thermoresponsive ion channel known as TRPA1 (subfamily A, member 1) is activated by temperatures below 18 °C (64 °F), which are usually reported as painful. Warm receptors are continuously active at constant temperatures above neutral skin temperature and have response maxima around 41–46 °C (106–115 °F), although, in many cases,…
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