von Hippel-Lindau disease

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von Hippel-Lindau disease

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effect on brain

In nervous system disease: Neurocutaneous syndromes
Von Hippel-Lindau disease results in tumours of blood vessels in the brain, especially in the cerebellum and retina, and in other organs.
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work of Kaelin

In William G. Kaelin, Jr.
…rare familial cancer known as von Hippel-Lindau (VHL) syndrome, which is caused by mutations in the VHL gene. Persons with VHL develop tumours in different parts of the body, including the central nervous system, the kidneys, and the pancreas, usually beginning in young adulthood. Kaelin observed that tumour growth in…
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