Louis Pasteur, (born Dec. 27, 1822, Dole, France—died Sept. 28, 1895, Saint-Cloud, near Paris), French chemist and microbiologist. Early in his career, after studies at the École Normale Supérieure, he researched the effects of polarized light on chemical compounds. In 1857 he became director of scientific studies at the École. His studies of fermentation of alcohol and milk (souring) showed that yeast could reproduce without free oxygen (the Pasteur effect); he deduced that fermentation and food spoilage were due to the activity of microorganisms and could be prevented by excluding or destroying them. His work overturned the concept of spontaneous generation (life arising from nonliving matter) and led to heat pasteurization, allowing vinegar, wine, and beer to be produced and transported without spoiling. He saved the French silk industry by his work on silkworm diseases. In 1881 he perfected a way to isolate and weaken germs, and he went on to develop vaccines against anthrax in sheep and cholera in chickens, following Edward Jenner’s example. He turned his attention to researching rabies, and in 1885 his inoculating with a weakened virus saved the life of a boy bitten by a rabid dog. In 1888 he founded the Pasteur Institute for rabies research, prevention, and treatment.
Louis Pasteur Article
Louis Pasteur summary
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rabies Summary
Rabies, acute, ordinarily fatal, viral disease of the central nervous system that is usually spread among domestic dogs and wild carnivorous animals by a bite. All warm-blooded animals, including humans, are susceptible to rabies infection. The virus, a rhabdovirus, is often present in the salivary
anthrax Summary
Anthrax, acute, infectious, febrile disease of animals and humans caused by Bacillus anthracis, a bacterium that under certain conditions forms highly resistant spores capable of persisting and retaining their virulence for many years. Although anthrax most commonly affects grazing animals such as
vaccine Summary
Vaccine, suspension of weakened, killed, or fragmented microorganisms or toxins or other biological preparation, such as those consisting of antibodies, lymphocytes, or messenger RNA (mRNA), that is administered primarily to prevent disease. A vaccine can confer active immunity against a specific
microbiology Summary
Microbiology, study of microorganisms, or microbes, a diverse group of generally minute simple life-forms that include bacteria, archaea, algae, fungi, protozoa, and viruses. The field is concerned with the structure, function, and classification of such organisms and with ways of both exploiting