chaulmoogra oil
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Hydnocarpus
- In Malpighiales: Achariaceae
…Hydnocarpus are a source of chaulmoogra oil, at one time important in the treatment of leprosy. The presumed active agent in the oil, hydnocarpic acid, is believed to have antibiotic properties. The seeds of Caloncoba echinata, from west-central Africa, are the source of gorli oil, also used in the treatment…
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leprosy
- In leprosy: History
…reported the possible utility of chaulmoogra oil in treating leprosy, and by the 1920s the oil or derivatives of the oil were the principal medication available. However, the drug was not effective when applied locally to affected areas, produced nausea when taken orally, and caused pain upon injection. Its real…
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medicinal use
- In history of medicine: China
Chaulmoogra oil was used by the Chinese for leprosy from at least the 14th century, and about the 19th century it began to be used for this purpose by Western physicians. The herb mahuang (Ephedra vulgaris) has been used in China for at least 4,000…
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