An important new dimension was added to cuneiform studies in the early years of the 20th century, through the discovery in 1906 of the royal archives of the Hittites at the ancient capital site of Hattusas, near the Turkish village of Boğazköy, east of Ankara. Some years earlier the existence of an Indo-European idiom in some cuneiform letters found in the Egyptian diplomatic archives of the 18th dynasty at Tell el-Amarna had been suspected by Johan Knudtzon. This unlikely surmise was confirmed by Friedrich Hrozný during World War I, when his initial interpretation of the Boğazköy materials proved that the predominant language in the thousands of tablets was that of the Indo-European Hittites, whose rule in central Asia Minor filled most of the 2nd millennium. The tablets offered no serious cryptological problems, being edited in a type of borrowed Akkadian cuneiform. The interpretation of the unknown language was aided by the partial ideographic nature of the script, which revealed elements of meaning independent of linguistic factors. Even more important was a series of bilingual parallel texts, in which the Akkadian versions served as a clue to the analysis of linguistic structure.

In the absence of close affinity to known languages, which vouches adequate safeguards against the notoriously misleading comparative method of interpretation, inner analysis of the unknown language is the only trustworthy procedure. Hurrian and Urartian are definitely related languages, but neither may yet be safely used to explain the other. Urartian has been solved to some extent with the help of its rather free use of ideograms and the Assyrian versions of two bilingual inscriptions.

Excavations at Ras Shamra in 1929 unearthed the remains of Ugarit. Inscriptions in an unknown simple system of cuneiform were found; the low number of 30 different signs pointed to an alphabetic type. The use of a vertical stroke as word-divider facilitated the decipherment, which was based on the correct assumption that an early North Semitic Canaanite dialect was involved. Thus the script was solved with astonishing speed by Hans Bauer, Edouard Dhorme, and Charles Virolleaud, yielding a Semitic dialect named Ugaritic, closely related to Old Phoenician. Hurrian inscriptions in the same script were also found, as were texts in conventional Middle Babylonian cuneiform.