hematopoietic stem cell

biology
Also known as: HSC

Learn about this topic in these articles:

bone marrow tranplant

  • autologous bone marrow transplant
    In bone marrow transplant: Autologous and allogeneic transplants

    …of stem cell therapy, since hematopoietic stem cells from the bone marrow are central to the recovery of the patient receiving the graft. An autologous transplant is used primarily in the case of cancer patients who are preparing to undergo high doses of chemotherapy or radiation therapy. Autologous transplant involves…

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cryopreservation

  • cryopreservation; cells
    In cryopreservation

    …the freezing and storage of hematopoietic stem cells, which are found in the bone marrow and peripheral blood. In autologous bone-marrow rescue, hematopoietic stem cells are collected from a patient’s bone marrow prior to treatment with high-dose chemotherapy. Following treatment, the patient’s cryopreserved cells are thawed and infused back into…

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formation of blood

  • blood components diagram
    In blood: Blood cells

    …interleukin-3, stimulates the most ancestral hematopoietic stem cell. Further differentiation of this stem cell into specialized descendants requires particular kinds of CSFs; for example, the CSF erythropoietin is needed for the maturation of red cells, and granulocyte CSF controls the production of granulocytes. These glycoproteins, as well as other CSFs,…

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stem cell research

  • neural and hematopoietic stem cells
    In stem cell: Bone marrow and hematopoietic stem cells

    Bone marrow contains cells called hematopoietic stem cells, which generate all the cell types of the blood and the immune system. Hematopoietic stem cells are also found in small numbers in peripheral blood and in larger numbers in umbilical cord blood. In…

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  • The ability of neural stem cells (NSCs) to give rise to motor neurons is especially promising in the realm of therapeutics. Once scientists understand how to control NSC differentiation, these cells may be safely used in the treatment of motor neuron diseases and spinal cord injuries.
    In neural stem cell

    …has also been research into hematopoietic stem cells (HSCs), which usually differentiate into blood cells but can also be transdifferentiated into neural lineages. These HSCs can be found in bone marrow, umbilical cord blood, and peripheral blood cells. Interestingly, these cells have been found to be spontaneously mobilized by certain…

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treatment of multiple sclerosis

  • In multiple sclerosis: Treatment of multiple sclerosis

    …the administration of immunosuppressive drugs, hematopoietic stem cells are harvested from the patient’s blood or bone marrow. These cells are then frozen and stored for later reinfusion into the patient following immunosuppressive therapy. Because hematopoietic stem cells have the potential to develop into normally functioning lymphocytes, transplant provides the patient’s…

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