limb bud

…body conical protrusions called the limb buds, which, once formed, possess all the materials necessary for limb development. Limb buds may be transplanted into various positions on the body or on the head and there develop into clearly recognizable limbs, conforming to their origin, whether a forelimb or hindlimb, a…

Limb buds have elongated markedly and become flattened at their outer ends. A constriction on each bud separates a paddlelike hand plate or foot plate from a cylindrical segment attached to the body wall. Predictably, the upper limbs are somewhat further advanced than the lower…

…formation and development of the limb bud from about the fourth to the eighth week of intrauterine life.

…to develop in the primitive limb bud in the core of mesenchyme that is derived directly from the unsegmented somatopleuric mesoderm. This mesenchyme condenses to form the blastemal masses of the future limb bones. Soon the mesenchyme becomes transformed into the cartilaginous precursors of the individual bones (except in the…