Ask the Chatbot Games & Quizzes ProCon History & Society Science & Tech Biographies Animals & Nature Geography & Travel Arts & Culture Money Videos
noncompetitive inhibition
Directory
References
Discover
A Factory Interior, watercolor, pen and gray ink, graphite, and white goache on wove paper by unknown artist, c. 1871-91; in the Yale Center for British Art. Industrial Revolution England
Inventors and Inventions of the Industrial Revolution
Shadow of a man holding large knife in his hand inside of some dark, spooky buiding
7 of History's Most Notorious Serial Killers
Young boys working in a thread spinning mill in Macon, Georgia, 1909. Boys are so small they have to climb onto the spinning frame to reach and fix broken threads and put back empty bobbins. Child labor. Industrial revolution
The Rise of the Machines: Pros and Cons of the Industrial Revolution
New York NY/ USA- November 23, 2018 Hordes of shoppers throng the Macy's Herald Square flagship store in New York looking for bargains on the day after Thanksgiving, Black Friday.
Why Is It Called Black Friday?
Secret Service Agent Listens To Earpiece
Secret Service Code Names of 11 U.S. Presidents
Mona Lisa, oil on wood panel by Leonardo da Vinci, c. 1503-06; in the Louvre, Paris, France. 77 x 53 cm.
Why Is the Mona Lisa So Famous?
Adolf Hitler (Nazi, nazism, German leader).
9 Things You Might Not Know About Adolf Hitler

noncompetitive inhibition

biochemistry

Learn about this topic in these articles:

property of enzymes

  • In the induced-fit theory of enzyme-substrate binding, a substrate approaches the surface of an enzyme (step 1 in box A, B, C) and causes a change in the enzyme shape that results in the correct alignment of the catalytic groups (triangles A and B; circles C and D represent substrate-binding groups on the enzyme that are essential for catalytic activity). The catalytic groups react with the substrate to form products (step 2). The products then separate from the enzyme, freeing it to repeat the sequence (step 3). Boxes D and E represent examples of molecules that are too large or too small for proper catalytic alignment. Boxes F and G demonstrate binding of an inhibitor molecule (I and I′) to an allosteric site, thereby preventing interaction of the enzyme with the substrate. Box H illustrates binding of an allosteric activator (X), a nonsubstrate molecule capable of reacting with the enzyme.
    In enzyme: Factors affecting enzyme activity

    Noncompetitive inhibition occurs when an inhibitor binds to the enzyme at a location other than the active site. In some cases of noncompetitive inhibition, the inhibitor is thought to bind to the enzyme in such a way as to physically block the normal active site.…

    Read More
  • In inhibition

    …at some other site (noncompetitive inhibition). In the latter, the inhibitor does not prevent binding of the substrate to the enzyme but sufficiently changes the shape of the site at which catalytic activity occurs so as to prevent it.

    Read More