Sucrose, or common table sugar, is a major commodity worldwide. By the second decade of the 21st century, its world production had amounted to more than 170 million tons annually. The unusual type of linkage between the two anomeric hydroxyl groups of glucose and fructose means that neither a free aldehyde group (on the glucose moiety) nor a free keto group (on the fructose moiety) is available to react unless the linkage between the monosaccharides is destroyed; for this reason, sucrose is known as a nonreducing sugar. Sucrose solutions do not exhibit mutarotation, which involves formation of an asymmetrical centre at the aldehyde or keto group. If the linkage between the monosaccharides composing sucrose is broken, the optical rotation value of sucrose changes from positive to negative; the new value reflects the composite rotation values for d-glucose, which is dextrorotatory (+52°), and d-fructose, which is levorotatory (−92°). The change in the sign of optical rotation from positive to negative is the reason sucrose is sometimes called invert sugar.

The commercial preparation of sucrose takes advantage of the alkaline stability of the sugar, and a variety of impurities are removed from crude sugarcane extracts by treatment with alkali. After this step, syrup preparations are crystallized to form table sugar. Successive “crops” of sucrose crystals are “harvested,” and the later ones are known as brown sugar. The residual syrupy material is called either cane final molasses or blackstrap molasses; both are used in the preparation of antibiotics, as sweetening agents, and in the production of alcohol by yeast fermentation. Sucrose is formed following photosynthesis in plants by a reaction in which sucrose phosphate first is formed.

The disaccharide trehalose is similar in many respects to sucrose but is much less widely distributed. It is composed of two molecules of α-d-glucose and is also a nonreducing sugar. Trehalose is present in young mushrooms and in the resurrection plant (Selaginella); it is of considerable biological interest because it is also found in the circulating fluid (hemolymph) of many insects. Since trehalose can be converted to a glucose phosphate compound by an enzyme-catalyzed reaction that does not require energy, its function in hemolymph may be to provide an immediate energy source, a role similar to that of the carbohydrate storage forms (i.e., glycogen) found in higher animals.

Lactose and maltose

Lactose is one of the sugars (sucrose is another) found most commonly in human diets throughout the world; it constitutes about 7 percent of human milk and about 4–5 percent of the milk of mammals such as cows, goats, and sheep. Lactose consists of two aldohexoses—β-d-galactose and glucose—linked so that the aldehyde group at the anomeric carbon of glucose is free to react; i.e., lactose is a reducing sugar.

A variety of metabolic disorders related to lactose may occur in infants; in some cases, they are the result of a failure to metabolize properly the galactose portion of the molecule.

Although not found in uncombined form in nature, the disaccharide maltose is biologically important because it is a product of the enzymatic breakdown of starches during digestion. Maltose consists of α-d-glucose linked to a second glucose unit in such a way that maltose is a reducing sugar. Maltose, which is readily hydrolyzed to glucose and can be metabolized by animals, is employed as a sweetening agent and as a food for infants whose tolerance for lactose is limited.