Voltaire: Later travels of Voltaire: …the morality of theatrical performances, Lettre à d’Alembert sur les spectacles (1758). Rousseau’s view that drama might well be abolished marked a final break between the two writers.

Voltaire: Achievements at Ferney of Voltaire: …dramatist, and dispatched an abusive Lettre à l’Académie. He never ceased to acknowledge a degree of genius in Shakespeare, yet spoke of him as “a drunken savage.” He returned to a strict classicism in his last plays, but in vain, for the audacities of his own previous tragedies, timid as…

Jean Racine: Life: …a stinging open letter entitled Lettre à l’auteur des Hérésies imaginaires et des deux visionnaires (1666; “Letter to the Author of the Pretended Heresies and the Two Enthusiasts”).

Yambo Ouologuem: …of his poems, and his Lettre à la France nègre (1969) attacks the “noble” sentiments that have been expressed by paternalistic French liberals about Africa.

Pierre Choderlos de Laclos: His Lettre à MM. de l’Académie Française sur l’éloge de M. le Maréchal de Vauban (1786) mocked the French army and its hopelessly outdated methods of defense and, as a result, lost him his army commission. He then entered politics, working for a while as secretary…

Antoine de Saint-Exupéry: …Lettre à un otage (1943; Letter to a Hostage), a call to unity among Frenchmen, and Le Petit Prince (1943; The Little Prince), a child’s fable for adults, with a gentle and grave reminder that the best things in life are still the simplest ones and that real wealth is…

Dominique Rolin: Inspired by Franz Kafka, Lettre au vieil homme (1973; “Letter to the Old Man”) focuses on the father figure, a process repeated in Dulle Griet (1977), in which the father’s death triggers a host of memories. Deux (1975; “Two”) dramatizes a conflict between woman and writer represented by two…

Georges Bernanos: …his Lettre aux Anglais (1942; Plea for Liberty, 1944) influenced his compatriots during World War II. A return to France in 1945 brought disillusionment with his country’s lack of spiritual renewal, and he lived thereafter in Tunis until he returned to France suffering from his final illness. Shortly before his…

calligraphy: The black-letter, or Gothic, style (9th to 15th century): …vernacular books—is called cursiva bastarda, lettre bâtarde, or simply bâtarde, the word bastard indicating its mixed parentage of formal black letter and casual cursive script. Although the script is not truly cursive (there are several pen lifts within and between letters), the freedom with which it is written (e.g., in…

The Horla, short story by Guy de Maupassant that is considered a masterly tale of the fantastic. The story was originally published as “Lettre d’un fou” (“Letter from a Madman”) in 1885 and was revised, retitled “Le Horla,” and published again in October 1886; the third and definitive version was

calligraphy: The black-letter, or Gothic, style (9th to 15th century): …to its generic name of textura. In some books the more formal black-letter looks stiff and narrow, and the lines forming the letters attain the perfect regularity of a picket fence; the rigidity is relieved only by hairlines made with the corner of the square-cut nib, which add a playful…

lettre de cachet: …reserved the right to grant lettres de grâce, or pardons, to persons who had been convicted by the courts.

Parlement: …to order it in a letter or appear in person before the Parlement in a special session called the lit de justice (literally “bed of justice,” a term originally used to describe the seat occupied by the king in these proceedings), where his presence would suspend any delegation of authority…

black letter: …black-letter cursive is the 17th-century lettre financière, which became an officially approved script under the patronage of Louis XIV.

black letter: Lettre françoise was another cursive black-letter style of script that was used in France during the Middle Ages. During the Renaissance it became a printing type, cut by the Parisian artist Robert Granjon. The typeface became known as civilité because it was used to print…

Molière: Molière’s unique sense of the comic: …Molière’s own name), and the Lettre sur la comédie de l’Imposteur of 1667. The placets and preface are aesthetically disappointing, since Molière was forced to fight on ground chosen by his opponents and to admit that comedy must be didactic. (There is no other evidence that Molière thought this, so…

Denis Diderot: The Encyclopédie: …Lettre sur les aveugles (An Essay on Blindness), remarkable for its proposal to teach the blind to read through the sense of touch, along lines that Louis Braille was to follow in the 19th century, and for the presentation of the first step in his evolutionary theory of survival…

Denis Diderot: The Encyclopédie: In 1751 he published his Lettre sur les sourds et muets (“Letter on the Deaf and Dumb”), which studies the function of language and deals with points of aesthetics, and in 1754 he published the Pensées sur l’interprétation de la nature (“Thoughts on the Interpretation of Nature”), an influential short…

Marcel Prévost: His Lettres à Françoise (1902; “Letters to Françoise”), Lettres à Françoise mariée (1908; “Letters to Françoise, Married”), and Françoise maman (1912; “Françoise, Mama”)—books of wise counsel to young girls—were even more widely read than his novels. He was elected to the Académie Française in 1909.

Marcel Prévost: …Françoise (1902; “Letters to Françoise”), Lettres à Françoise mariée (1908; “Letters to Françoise, Married”), and Françoise maman (1912; “Françoise, Mama”)—books of wise counsel to young girls—were even more widely read than his novels. He was elected to the Académie Française in 1909.

Honoré de Balzac: Early career: …her by correspondence; the resulting Lettres à l’étrangère (“Letters to a Foreigner”), which appeared posthumously (4 vol., 1889–1950), are an important source of information for the history both of Balzac’s life and of his work.

history of logic: Other 18th-century logicians: …mathematician Leonhard Euler in his Lettres à une princesse d’Allemagne (1768–74; “Letters to a German Princess”). These techniques and the related Venn diagrams have been especially popular in logic education. In Euler’s method the interior areas of circles represented (intensionally) the more basic concepts making up a concept or property.…

Claude Autant-Lara: …1942—Le Mariage de Chiffon and Lettres d’amour—prefigured his work in Le Diable au corps and strengthened his standing as one of the major exponents of the French cinema’s “tradition of quality.” Adapted from a novel by Raymond Radiguet, Le Diable au corps is the story of an adolescent boy’s affair…

Henri de Saint-Simon: Life.: In his first published work, Lettres d’un habitant de Genève à ses contemporains (1803; “Letters of an Inhabitant of Geneva to His Contemporaries”), Saint-Simon proposed that scientists take the place of priests in the social order. He argued that the property owners who held political power could hope to maintain…

Alfred de Musset: His Lettres de Dupuis et Cotonet (1836–37), for example, contain a brilliant and illuminating satire of the literary fashions of the day. A love affair with the novelist George Sand that went on intermittently from 1833 to 1839 inspired some of his finest lyrics, as recounted…

René Philombe: …Lettres de ma cambuse (1964; Tales from My Hut, 1977), which he had written in 1957, won the Prix Mottard of the Académie Française. His other published works include Sola, ma chérie (1966; “Sola, My Darling”), a novel about seemingly unjust marriage customs; Un Sorcier blanc à Zangali (1970; “A…

Alphonse Daudet: Life: …recalled in passages of his Lettres de mon moulin (1869; “Letters from My Mill”). His full social life over the years 1863–65 (until Morny’s death) provided him with the material that he analyzed mercilessly in Le Nabab (1877; “The Nabob”). In January 1867 he married Julia Allard, herself a writer…

Assizes of Jerusalem, a law code based on a series of customs and practices that developed in the Latin crusader kingdom of Jerusalem in the 12th century. It stands as one of the most complete monuments of feudal law. The basis for the assizes was laid by Godfrey of Bouillon (d. 1100), first ruler

Jean-Jacques Rousseau: Years of seclusion and exile of Jean-Jacques Rousseau: …écrites de la montagne (1764; Letters Written from the Mountain). No longer, as in the Discourse on the Origin of Inequality, was Geneva depicted as a model republic but as one that had been taken over by “twenty-five despots”; the subjects of the king of England were said to be…

Blaise Pascal: Les Provinciales of Blaise Pascal: Written in defense of Antoine Arnauld, an opponent of the Jesuits and a defender of Jansenism who was on trial before the faculty of theology in Paris for his controversial religious works, Pascal’s 18 Lettres écrites par Louis de Montalte à…

Montesquieu: Early life and career: …publishing his Lettres persanes (Persian Letters, 1722), in which he gave a brilliant satirical portrait of French and particularly Parisian civilization, supposedly seen through the eyes of two Persian travellers. This exceedingly successful work mocks the reign of Louis XIV, which had only recently ended; pokes fun at all…

Voltaire: Return to France: …work of incisive brevity: the Lettres philosophiques (1734). These fictitious letters are primarily a demonstration of the benign effects of religious toleration. They contrast the wise Empiricist psychology of Locke with the conjectural lucubrations of René Descartes. A philosopher worthy of the name, such as Newton, disdains empty, a priori

Pyotr Yakovlevich Chaadayev: …afterward writing in French his Lettres philosophiques (1827–31; “Philosophical Letters”), which posed the problem of Russia’s relation to the West; articulated a ruthless criticism of Russian history, culture, and the Orthodox religion; and advocated assimilation of Roman Catholicism and western European culture. The first letter of this work had circulated…

Mariana Alcoforado: …long believed to have written Lettres portugaise (1669; “Portuguese Letters”), a collection of five love letters, though most modern authorities reject her authorship.

Blaise Pascal: Les Provinciales of Blaise Pascal: Written in defense of Antoine Arnauld, an opponent of the Jesuits and a defender of Jansenism who was on trial before the faculty of theology in Paris for his controversial religious works, Pascal’s 18 Lettres écrites par Louis de Montalte à…

Jean-Georges Noverre: …French choreographer whose revolutionary treatise, Lettres sur la danse et sur les ballets (1760), still valid, brought about major reforms in ballet production, stressing the importance of dramatic motivation, which he called ballet d’action, and decrying overemphasis on technical virtuosity. His first choreographic success, Les Fêtes chinoises (1754), attracted the…

Voltaire: Return to France: …work of incisive brevity: the Lettres philosophiques (1734). These fictitious letters are primarily a demonstration of the benign effects of religious toleration. They contrast the wise Empiricist psychology of Locke with the conjectural lucubrations of René Descartes. A philosopher worthy of the name, such as Newton, disdains empty, a priori

Isabelle de Charrière: …opposed to revolutionary radicalism (Lettres trouvées sous la neige, 1794; “Letters Found on the Snow”). Her novels, of which the most important were Caliste; ou, lettres écrites de Lausanne (1786; “Caliste; or, Letters Written from Lausanne”) and Lettres neuchâteloises (1784; “Letters of Neuchâtel”), abound in philosophical reflection, refined psychological…

Tracy Letts is an American actor and dramatist who was best known for his award-winning play August: Osage County (2007; film 2013). Letts was raised in Durant, Oklahoma, the home of Southeastern Oklahoma State University. His father, Dennis, was an English professor and an aspiring actor, and his

Tracy Letts is an American actor and dramatist who was best known for his award-winning play August: Osage County (2007; film 2013). Letts was raised in Durant, Oklahoma, the home of Southeastern Oklahoma State University. His father, Dennis, was an English professor and an aspiring actor, and his

lettuce, (Lactuca sativa), annual leaf vegetable of the aster family (Asteraceae). Most lettuce varieties are eaten fresh and are commonly served as the base of green salads. Lettuce is generally a rich source of vitamins K and A, though the nutritional quality varies, depending on the variety.

Clarence Brown: The 1930s: Letty Lynton starred Crawford as a woman unjustly accused of murder, and The Son-Daughter was a romance set in San Francisco’s Chinatown, with Helen Hayes, Ramon Novarro, and Warner Oland. In 1933 Brown directed the Depression-era drama Looking Forward, about a store owner (Lewis Stone)…

Luxembourg, landlocked country in northwestern Europe. One of the world’s smallest countries, it is bordered by Belgium on the west and north, France on the south, and Germany on the northeast and east. Luxembourg has come under the control of many states and ruling houses in its long history, but

Luxembourgish language, national language of Luxembourg. Luxembourgish is a Moselle-Franconian dialect of the West Middle German group. This old language has been enriched by many French words and phrases, and the resulting dialect is spoken by all classes of people in Luxembourg. The population of

Luxembourg: Independent Luxembourg: …by the CSV and the Socialist Workers’ Party of Luxembourg (Lëtzebuergesch Sozialistesch Arbechterpartei; LSAP). In 2000, at age 79, Grand Duke Jean formally abdicated as chief of state and was replaced by his son, Crown Prince Henri, who in 2001 became the first member of the Luxembourgian royal family to…

Luxembourg, city, capital of Luxembourg, located in the south-central part of the country. Luxembourg city is situated on a sandstone plateau into which the Alzette River and its tributary, the Petrusse, have cut deep winding ravines. Within a loop of the Alzette, a rocky promontory called the Bock

Luxembourgish language, national language of Luxembourg. Luxembourgish is a Moselle-Franconian dialect of the West Middle German group. This old language has been enriched by many French words and phrases, and the resulting dialect is spoken by all classes of people in Luxembourg. The population of

Helmut Käutner: …is Die letzte Brücke (1954; The Last Bridge), which won the International Jury Prize at the Cannes Film Festival. Käutner’s success during this period won him a contract with Universal Pictures in 1957. His two American-made films were the family melodrama The Restless Years (1958) and A Stranger in My…

Karl von Holtei: …Vagabunden (1851; “The Vagabonds”) and Der letzte Komödiant (1863; “The Last Comedian”), that are interesting when they draw on his own experience but suffer from loose construction and superficial characterization. As a reciter he was unequalled, especially in his interpretation of speeches from Shakespeare. After 1850 he grew tired of…

history of film: Germany: …was Der letzte Mann (The Last Laugh, 1924), a film in the genre of Kammerspiel (“intimate theatre”), that made him world-famous. Scripted by Carl Mayer and produced by Erich Pommer for UFA, Der letzte Mann told the story of a hotel doorman who is humiliated by the loss of…

Karl Kraus: …the lengthy satirical drama Die letzten Tage der Menschheit (1918; published 1922; “The Last Days of Mankind”), a visionary condemnation of the futility of World War I.

study of religion: Psychological studies: …examples, was the American psychologist James H. Leuba (1868–1946). In A Psychological Study of Religion he attempted to account for mystical experience psychologically and physiologically, pointing to analogies with certain drug-induced experiences. Leuba argued forcefully for a naturalistic treatment of religion, which he considered to be necessary if religious psychology…

history of Europe: Changing centres of wealth: Leubingen, for example, was a 28-foot- (8.5-metre-) high barrow with an elaborately constructed 66-foot-wide central stone cairn delineated by a ring ditch. The cairn covered and protected a thatched tentlike wooden structure made of large oak planks with gypsum mortar in the cracks. The skeleton…

fynbos: …heathers (Erica) and proteoids, especially Leucadendron and Protea. The flowers of this extraordinarily diverse flora are pollinated by both insects (but few butterflies) and nectar-eating birds, such as sunbirds (Nectarina) and the Cape sugarbird (Promerops cafer)—animals with which the proteoids have coevolved. Seed dispersal by

Leucas: …trial by ordeal (the “Leucadian leap”) for accused persons, survivors being picked up by boat. According to legend, Sappho, desperate with love, ended her life there. Economic activities include considerable olive-oil production but meagre cereal cultivation. The currant, introduced about 1859, has been one of the chief cash crops.…

Fabales: Ecological and economic importance: Various forms of leucaena (such as Leucaena leucocephala) have been developed for animal forage, firewood, and construction, as well as for the high production of nitrogen that enriches impoverished soils, especially in the Asiatic tropics. Other important plants are acacia, used for animal food (both pods and leaf…

daisy: The cultivated Shasta daisy resembles the oxeye daisy but has larger flower heads that may reach a diameter of 10 cm (4 inches).

oxeye daisy, (Leucanthemum vulgare), perennial plant in the aster family (Asteraceae), commonly grown as an ornamental. The oxeye daisy is native to Europe and Asia and has naturalized in the United States. The plant grows about 60 cm (2 feet) high and has notched oblong leaves and long petioles

Leucas, Greek island in the Ionian Sea (Modern Greek: Ióvio Pélagos). It constitutes a dímos (municipality) and with the island of Meganísi forms the perifereiakí enótita (regional unit) of Levkás in the Ionian Islands (Iónia Nisiá) periféreia (region), western Greece. The 117-square-mile

cisco, herringlike type of whitefish

leucine, an amino acid obtainable by the hydrolysis of most common proteins. Among the first of the amino acids to be discovered (1819), in muscle fibre and wool, it is present in large proportions (about 15 percent) in hemoglobin (the oxygen-carrying pigment of red blood cells) and is one of

Achilles Tatius: …Alexandria) was the author of Leucippe and Cleitophon, one of the Greek prose romances that influenced the development of the novel centuries later. Nothing certain is known of Achilles’ life. Some Byzantine sources called him a rhetor (“teacher of rhetoric”). In the Suda lexicon of the 10th century ad, he…

Leucippus was a Greek philosopher credited by Aristotle and by Theophrastus with having originated the theory of atomism. It has been difficult to distinguish his contribution from that of his most famous pupil, Democritus. Only fragments of Leucippus’ writings remain, but two works believed to

Anton Francesco Grazzini was an Italian poet, playwright, and storyteller who was active in the linguistic and literary controversies of his day. Apparently educated in vernacular literature, Grazzini in 1540 took part in the founding of the Accademia degli Umidi (“Academy of the Humid”), the first

chub: The European chub (Leuciscus cephalus) is a popular, though not especially palatable, game fish found in Europe and Great Britain, primarily in rivers. A large-mouthed fish with large, black-edged scales, it attains a maximum length and weight of about 60 cm (2 feet) and 7–8 kg…

ide, (Leuciscus idus), common sport and food fish of the carp family, Cyprinidae, widely distributed in rivers and lakes of Europe and western Siberia. An elongated, rather stout fish, the ide is blue-gray or blackish with silvery sides and belly and is usually about 30–50 cm (12–20 inches) long.

dace: …and Europe, the dace is Leuciscus leuciscus, a relative of the chub. Usually found in moderately swift streams and rivers, the European dace is a rather small-headed, silvery fish attaining a usual length and weight of 25–30 cm (10–12 inches) and 0.5–0.7 kg (1–1 12 pounds). It lives in schools…

leucite, one of the most important feldspathoid minerals, a potassium aluminosilicate (KAlSi2O6). It occurs only in igneous rocks, particularly potassium-rich, silica-poor, recent lavas. Some important localities include Rome; Uganda; and Leucite Hills, Wyo., U.S. Leucite is used as a fertilizer in

leucitite, extrusive igneous rock, coloured ash gray to nearly black, that contains leucite and augite as large, single crystals (phenocrysts) in a fine-grained matrix (groundmass) of leucite, augite, sanidine, apatite, titanite, magnetite, and melilite; in this regard it is similar to nephelinite,

Rudolf Leuckart was a German zoologist and teacher who initiated the modern science of parasitology. He described the complicated life histories of various parasites, including tapeworms and the liver fluke, and demonstrated that some human diseases, such as trichinosis, are caused by multicellular

Rudolf Leuckart was a German zoologist and teacher who initiated the modern science of parasitology. He described the complicated life histories of various parasites, including tapeworms and the liver fluke, and demonstrated that some human diseases, such as trichinosis, are caused by multicellular

cushion moss, any of the plants of the genus Leucobryum (subclass Bryidae), which form tufts resembling giant grayish white pincushions in moist woods or swampy areas. Three or more species are native to North America. Cushion moss grows in dense clumps ranging from a few centimetres to a metre (1

mimicry: Parasitic worms: One species, Leucochloridium macrostomum, resides principally in the intestine of songbirds. The eggs of the parasite pass to the outside in the feces of the birds and are readily ingested by a terrestrial snail, Succinea, an inhabitant of waterlogged meadows and riverbanks. The

igneous rock: Mineralogical components: …to as such or as leucocratic. The mafic minerals include olivine, pyroxenes, amphiboles, and biotites, all of which are dark in colour. Mafic minerals are said to be melanocratic. These terms can be applied to the rocks, depending on the relative proportion of each type of mineral present. In this…

white blood cell, a cellular component of the blood that lacks hemoglobin, has a nucleus, is capable of motility, and defends the body against infection and disease by ingesting foreign materials and cellular debris, by destroying infectious agents and cancer cells, or by producing antibodies. In

dye: Vat dyeing: …to a soluble, colourless form, leucoindigo. After treatment in a leucoindigo bath, the fabric becomes coloured upon exposure to air; atmospheric oxygen regenerates indigo by oxidation.

snowflake, (genus Leucojum), small genus of flowering plants in the amaryllis family (Amaryllidaceae). Several species, including spring snowflake (Leucojum vernum) and summer snowflake (L. aestivum), are cultivated as garden flowers. The plants are closely related to snowdrops (genus Galanthus)

snowflake: …spring snowflake (Leucojum vernum) and summer snowflake (L. aestivum), are cultivated as garden flowers. The plants are closely related to snowdrops (genus Galanthus) and typically emerge from bulbs in early spring.

snowflake: Several species, including spring snowflake (Leucojum vernum) and summer snowflake (L. aestivum), are cultivated as garden flowers. The plants are closely related to snowdrops (genus Galanthus) and typically emerge from bulbs in early spring.

sponge: Water-current system: of canals—ascon, sycon, and leucon. The simplest, or ascon, type, found only in certain primitive genera of the Calcarea (e.g., Leucosolenia), is characterized by an arrangement of choanocytes around a central cavity that directly communicates with the osculum. The walls of these sponges are thin, lack canals, and are…

chromatophore: leucophores (white). The distribution of the chromatophores and the pigments they contain determine the colour patterns of an organism.

snowy egret, (Egretta thula), white New World egret (family Ardeidae). It is about 24 inches (60 cm) long and has filmy recurved plumes on the back and head. Formerly hunted for its plumes, it ranges from the United States to Chile and

skate: …little, or hedgehog, skate (Leucoraja erinacea) of the western Atlantic, for example, is adult at a length of 50–54 cm (20–21.3 inches) or less. In contrast, both the big skate (Beiringraja binoculata) of the eastern North Pacific Ocean and the common skate (Dipturus batis) of the western North Atlantic…

leukorrhea, flow of a whitish, yellowish, or greenish discharge from the vagina of the female that may be normal or that may be a sign of infection. Such discharges may originate from the vagina, ovaries, fallopian tubes, or, most commonly, the cervix. Leukorrhea may occur during pregnancy and is

Leucosolenia, genus of tubular branched sponges of the class Calcispongiae (phylum Porifera). Found in tide pools and on wharves and represented by numerous species, the widespread genus includes most of the asconoids, structurally the simplest sponges. Most species of Leucosolenia are 2.5

Leucosolenia, genus of tubular branched sponges of the class Calcispongiae (phylum Porifera). Found in tide pools and on wharves and represented by numerous species, the widespread genus includes most of the asconoids, structurally the simplest sponges. Most species of Leucosolenia are 2.5

fungus: Annotated classification: Order Leucosporidiales Mycoparasitic; mycelia lack clamp connections; septate basidia; example genera include Leucosporidiella, Leucosporidium, and Mastigobasidium. Order Sporidiales Nonpathogenic; basidia may be very long; hyphae with clamp connections; some species emit peachlike odour; example genera include Sporidiobolus

Leucothea, (Greek: White Goddess [of the Foam]), in Greek mythology, a sea goddess first mentioned in Homer’s Odyssey, in which she rescued the Greek hero Odysseus from drowning. She was customarily identified with Ino, daughter of the Phoenician Cadmus; because she cared for the infant god

Leucothoë, genus of about eight species of shrubs in the heath family (Ericaceae), native to North America and eastern Asia. Species such as highland doghobble (Leucothoë fontanesiana) are grown as ornamentals, chiefly for their foliage and attractive flowers. The plants grow to about 1.8 metres (6

Leucothoë: Species such as highland doghobble (Leucothoë fontanesiana) are grown as ornamentals, chiefly for their foliage and attractive flowers.

lobotomy, surgical procedure in which the nerve pathways in a lobe or lobes of the brain are severed from those in other areas. The procedure was formerly used as a radical therapeutic measure to help grossly disturbed patients with schizophrenia, manic depression and mania (bipolar disorder), and

Battle of Leuctra, (6 July 371 bce). Fought in Boeotia, Greece, the Battle of Leuctra made Thebes the leading military power among the Greek city-states, ending the long dominance of Sparta. The battle also marked a revolutionary advance in battlefield tactics and demonstrated the effectiveness of

Niklaus Leuenberger was a Swiss peasant hero, spokesman for rural discontent, and leader of the peasant revolt at Bern (1653), for which he earned the sobriquet King of the Peasants. By the mid-17th century, Swiss peasants had come to bitterly resent the domination of the towns and to openly

league, any of several European units of measurement ranging from 2.4 to 4.6 statute miles (3.9 to 7.4 km). In English-speaking countries the land league is generally accepted as 3 statute miles (4.83 km), although varying lengths from 7,500 feet to 15,000 feet (2.29 to 4.57 km) were sometimes

prostate cancer: Treatment: …using a procedure known as leukapheresis (the separation of leukocytes, or white blood cells, from other blood components). The APCs are then cultured in a laboratory, where they are grown in the presence of a protein that occurs on the surface of prostate cancer cells. This process results in APC…

Leucas, Greek island in the Ionian Sea (Modern Greek: Ióvio Pélagos). It constitutes a dímos (municipality) and with the island of Meganísi forms the perifereiakí enótita (regional unit) of Levkás in the Ionian Islands (Iónia Nisiá) periféreia (region), western Greece. The 117-square-mile

Latakia, city and muḥāfaẓah (governorate), northwestern Syria. The city, capital of the governorate, is situated on the low-lying Raʿs Ziyārah promontory that projects into the Mediterranean Sea. It was known to the Phoenicians as Ramitha and to the Greeks as Leuke Akte. Its present name is a

leukemia, a cancer of the blood-forming tissues characterized by a large increase in the numbers of white blood cells (leukocytes) in the circulation or bone marrow. A number of different leukemias are classified according to the course of the disease and the predominant type of white blood cell

stem cell: Mouse embryonic stem cells: …indefinitely in the presence of leukemia inhibitory factor (LIF), a glycoprotein cytokine. If cultured mouse embryonic stem cells are injected into an early mouse embryo at the blastocyst stage, they will become integrated into the embryo and produce cells that differentiate into most or all of the tissue types that…

Switzerland: Rural communities: … in the Rhine valley and Leukerbad in Valais canton are noted as spas. Valley forks, where the traffic from two valleys combines, were natural sites for settlement. Two of the best examples are Martigny (the Roman city of Octodurum), at the meeting of the Great Saint Bernard Pass route and…